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MAEKAWA Fumihiko

Researcher Name
MAEKAWA Fumihiko
Div (Section) name/title
Health and Environmental Risk Division（Health Effect Assessment Section）／Chief Senior Researcher
Research Subject
  • Fiscal Year: 2021
    • 25517 : Research on the health hazard assessment considering the real-life environment and vulnerability
    • 25625 : A fundamental study for evaluating health impact of environmental factors
    • 25686 : The influence of the exposure to metals on mice brain and behavior
    • 25687 : Elucidation of the molecular mechanism of acute encephalopathy by Sugihiratake and the application development
    • 25688 : Elucidation of the relationship between developmental dioxin exposure and cognitive decline in advanced age
  • Fiscal Year: 2020
    • 25099 : Research Program on Health and Environmental Safety
    • 25141 : Research Project on Health Impacts of Chemicals on Children and Future Generations
    • 25212 : To what degree is the neural circuit controlling aggression affected by environment?: Searching for the intersection of gene and environment.
    • 25213 : The influence of the exposure to metals on mice brain and behavior
    • 25214 : Elucidation of the molecular mechanism of acute encephalopathy by Sugihiratake and the application development
    • 25215 : Elucidation of the relationship between developmental dioxin exposure and cognitive decline in advanced age
    • 25236 : A Fundamental Study for Evaluating Health Impact of Environmental Factors
  • Fiscal Year: 2019
    • 24696 : Research Program on Health and Environmental Safety
    • 24721 : Research Project on Health Impacts of Chemicals on Children and Future Generations
    • 24817 : A comprehensive risk management and presentation of toxicity equivalency factors for unintentional brominated dioxin-like compounds
    • 24926 : A Fundamental Study for Evaluating Health Impact of Environmental Factors
    • 24928 : To what degree is the neural circuit controlling aggression affected by environment?: Searching for the intersection of gene and environment.
    • 24931 : The influence of the exposure to metals on mice brain and behavior
    • 24933 : Elucidation of the molecular mechanism of acute encephalopathy by Sugihiratake and the application development
    • 24934 : Elucidation of the relationship between developmental dioxin exposure and cognitive decline in advanced age
  • Fiscal Year: 2018
    • 24304 : Research project on health impacts of chemicals on children and future generations
    • 24355 : Research program on health and environmental safety
    • 24421 : A comprehensive risk management and presentation of toxicity equivalency factors for unintentional brominated dioxin-like compounds
    • 24450 : To what degree is the neural circuit controlling aggression affected by environment?: Searching for the intersection of gene and environment.
    • 24531 : A fundamental study for evaluating health impact of environmental factors
  • Fiscal Year: 2017
    • 23824 : Research project on health impacts of chemicals on children and future generations
    • 23847 : Research program on health and environmental safety
    • 23938 : Is sex chromosome-dependent brain sexual differentiation affected by environmental factors?
    • 23975 : A fundamental study for evaluating health impact of environmental factors
    • 24000 : A comprehensive risk management and presentation of toxicity equivalency factors for unintentional brominated dioxin-like compounds
  • Fiscal Year: 2016
    • 23414 : Research program on health and environmental safety
    • 23415 : Research project on health impacts of chemicals on children and future generations
    • 23579 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 23580 : Is sex chromosome-dependent brain sexual differentiation affected by environmental factors?
    • 23659 : A fundamental study for evaluating health impact of environmental factors
    • 23727 : A phylogenetic approach to brain focusing on sexual dimorphic nucleus
  • Fiscal Year: 2015
    • 23018 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 23116 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
    • 23118 : Is sex chromosome-dependent brain sexual differentiation affected by environmental factors?
    • 23173 : Analysis of vasopressin receptor functions to establish pharmacological approaches to developmental disorders
  • Fiscal Year: 2014
    • 22606 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22796 : The sex difference of retrotransposon expression in the brain and the relation to reproductive function.
    • 22802 : Establishment of multidisciplinary strategy toward comprehensive understanding of developmental neurotoxicity induced by environmental chemicals in house dust
  • Fiscal Year: 2013
    • 22190 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 22306 : The sex difference of retrotransposon expression in the brain and the relation to reproductive function.
    • 22307 : Feasibility study for establishment of method to assess developmental neurotoxicity in birds
    • 22475 : Exploration of molecular epidemiological indexes to health effects of environmental factors focusing on genetic and epigenetic mutation
    • 22496 : Establishment of Japanese quail standard inbred strains for toxicity testing of chemicals
    • 22544 : Establishment of an international cooperation for promoting arsenic research
  • Fiscal Year: 2012
    • 21761 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21986 : Studies of factors contributing to the regulation of epigenetics
    • 21987 : The sex difference of retrotransposon expression in the brain and the relation to reproductive function.
  • Fiscal Year: 2011
    • 21319 : Mechanism and evaluation system of the developmental health effects of environmental factors
    • 21480 : Studies of factors contributing to the regulation of epigenetics
    • 21481 : Studies on the mechanism of transcription factor dependent effects of environmental chemicals
    • 21484 : Development of new methods for detecting social impairments caused by environmental factors
  • Fiscal Year: 2010
    • 21051 : Studies to evaluate toxicityies of environmental chemicals focusing on their epigenetic effects
    • 21053 : Studies of factors contributing to the regulation of epigenetics
    • 21055 : Studies on the mechanism of transcription factor dependent effects of environmental chemicals
    • 21249 : Development of new methods for detecting social impairments caused by environmental factors
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Research Result (Publication)
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  • Original Paper
  • Review
  • Book
  • Other Publications
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    Presenter : Maekawa F., Nakamura K., Nakayama S.
    Title : , CHEMICALS IN THE ENVIRONMENT AND BRAIN DEVELOPMENT: IMPORTANCE OF NEUROENDOCRINOLOGICAL APPROACHES (2017)
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Research Result (Presentation)
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  • Research Presentation
  • Research Lecture
  • Research Presentation
    Locus coeruleus noradrenergic neurons are novel targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse brain
    Presenter : Kimura E., Kouda M., Maekawa F., Tohyama C.
    Name of Society : The Virtual 2021 SOT Annual Meeting (2021)
    Name of Proceedings : -
  • Research Presentation
    Detection of a behavioral endpoint related to developmental methylmercury exposure independent of experimental environment in mice
    Presenter : Maekawa F., Endo T., Kakeyama M.
    Name of Society : the 126th Annual Meeting of The Japanese Association of Anatomists/the 98th Annual Meeting of The Physiological Society of Japan (2021)
    Name of Proceedings : -
  • Research Presentation
    Uptake, clearance and metabolites of 2,3,7,8-tetrabrominateddibensofuran in mouse
    Presenter : Tue N.M., Kimura E., Maekawa F., Goto A., Kunisue T., Suzuki G.
    Name of Society : 39th International Symposium on Halogenated Persistent Organic Pollutants (2019)
    Name of Proceedings : Abstract Book, 829
  • Research Presentation
    Perinatal exposure to dioxins impacts on gene expression and infant behavior in the mouse
    Presenter : Kimura E., Suzuki G., Uramaru N., Maekawa F.
    Name of Society : NIPS international workshop “Sensing food/nutrient/environment toward integrative metabolic regulation” (2019)
    Name of Proceedings : Abstracts, 29
  • Research Lecture
    Early developmental exposure to environmental chemicals and energy metabolism
    Presenter : Maekawa F.
    Name of Society : NIPS international workshop “Sensing food/nutrient/environment toward integrative metabolic regulation” (2019)
    Name of Proceedings : Abstracts, 24
  • Research Lecture
    Estrogenic action by tris(2,6-dimethylphenyl) phosphate, an impurity in flame retardant formulations, impairs the development of female reproductive functions
    Presenter : Maekawa F., Sano K., Suzuki G., Matsukami H., Tsukahara S.
    Name of Society : The 3rd Sino-Japan Symposium on the frontier of Behavioral Neuroendocrinology (2019)
    Name of Proceedings : Abstracts
  • Research Presentation
    Common behavioral characteristics in the mice maternally exposed to different types of dioxins
    Presenter : Maekawa F., Kimura E., Uramaru N., Suzuki G.
    Name of Society : 9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress (2019)
    Name of Proceedings : -
  • Research Presentation
    Behavioral traits associated with neurodevelopmental disorders in the mice lacking both vasopressin 1a and 1b receptors
    Presenter : Maekawa F., Kimura E., Sano K., Endo T., Nakamura K.
    Name of Society : Neuroscience 2019 (2019)
    Name of Proceedings : -
  • Research Presentation
    Behavioral profile of mice genetically deficient in vasopressin 1a and/or 1b receptors in the IntelliCage
    Presenter : Maekawa F., Sano K., Kimura E., Nakamura K.
    Name of Society : 11th FENS Forum (2018)
    Name of Proceedings : -, C154
  • Research Presentation
    Investigation of gene expressions related to aggression in quail diencephalon
    Presenter : Maekawa F., Nagino K., Yang J., Htike N.T.T., Tsukahara S., Ubuka T., Tsutsui K., Kawashima T.
    Name of Society : The 95th Annual Meeting of the Physiological Society of Japan (2018)
    Name of Proceedings : Proceedings of the 95th Annual Meeting of the Physiological Society of Japan, S151
  • Research Presentation
    Developmental exposure to tetrabromobisphenol A (TBBPA) on late onset behavior and neurological biomarkers in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 40th Annual Meeting of the Japan Neuroscience Society (2017)
    Name of Proceedings : Abstract, 218
  • Research Lecture
    Experimental approaches toward understanding the association between early-life exposure to environmental chemicals and developmental disorders
    Presenter : Maekawa F.
    Name of Society : INTERNATIONAL SYMPOSIUM ON AUTISM 2017: CELEBRATING BRIMS 10TH YEAR ANNIVERSARY (2017)
    Name of Proceedings : Abstracts, 14-15
  • Research Presentation
    Effects of perinatal exposure to a phosphate ester flame retardant on novel object recognition ability and memory function-related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : 45th Myanmar Health Research Congress (2017)
    Name of Proceedings : Abstract, 120
  • Research Presentation
    Comprehensive analysis of house dust using GC×GC-HRTOFMS and in-house software
    Presenter : Ieda T., Hashimoto S., Takazawa Y., Tanabe K., Zushi Y., Shibata Y., Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Kawashima T.
    Name of Society : DIOXIN2016 (2016)
    Name of Proceedings : Abstracts
  • Research Presentation
    Developmental exposure to acetamiprid alters behavioral profile of male mice
    Presenter : Sano K., Yang J., Tin-Tin-Win-Shwe, Maekawa F.
    Name of Society : 10th FENS (the Federation of European Neuroscience Societies) Forum (2016)
    Name of Proceedings : Abstracts, (C076)
  • Research Presentation
    Perinatal exposure to a phosphate ester flame retardant affects memory function and related gene expression in adult mice
    Presenter : Tin-Tin-Win-Shwe, Sano K., Isobe T., Kawashima T., Suzuki G., Hashimoto S., Nakayama S., Maekawa F.
    Name of Society : The 5th Annual Meeting of The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) (2016)
    Name of Proceedings : Abstract(P-07), 40
  • Research Lecture
    Developmental exposure to a neonicotinoid affects certain behavioral parameters of mice in adulthood: Requirement of evaluation of socio-sexual and emotional behaviors using animal models
    Presenter : Maekawa F.
    Name of Society : Symposium on Systemic Pesticides Post-Neonics -What Next? (2016)
    Name of Proceedings : Abstracts
  • Research Presentation
    Evaluation of potentially developmentally neurotoxic chemicals using behavioral testing and neuroendocrinological analysis
    Presenter : Maekawa F., Sano K., Suzuki G., Nakayama S., Isobe T., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T.
    Name of Society : The 93rd Annual Meeting of the Physiological Society of Japan (2016)
    Name of Proceedings : Proceedings of The 93rd Annual Meeting of the Physiological Society of Japan, 66(supplement1):S73
  • Research Presentation
    Male aggressive and reproductive behaviors in long-term breeding closed colony NIES-L of Japanese quail
    Presenter : NAGINO K., Ubuka T., Tsutsui K., Maekawa F., Kawashima T.
    Name of Society : Avian Model Systems 9: A New Integrative Platform (2016)
    Name of Proceedings : Proceedings of Avian Model System 9: A New Integrative Platform, 115
  • Research Lecture
    In vivo evaluation of a flame retardant having estrogenic activity using mouse model
    Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
    Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
    Name of Proceedings : abstract, 1-4
  • Research Presentation
    Analysis of aggressive behavior in two Japanese quail strains and their gene expressions possibly related to aggression in the hypothalamus
    Presenter : Maekawa F., Nagino K., Yang J., Ubuka T., Tsutsui K., Kawashima T.
    Name of Society : 11th International Symposium on Avian Endocrinology (2016)
    Name of Proceedings : 11th International Symposium on Avian Endocrinology Abstracts, 68
  • Research Presentation
    Melanocortin Receptors and MRAP expression in the chick adrenal gland: correlating mRNA expression levels and ligand sensitivity of chick melanocortin receptors expressed in CHO cell
    Presenter : Dores R.M., Thomas A., Maekawa F., Kawashima T., Sakamoto H., Sukamoto T.
    Name of Society : 11th International Symposium on Avian Endocrinology (2016)
    Name of Proceedings : 11th International Symposium on Avian Endocrinology Abstracts, 60
  • Research Presentation
    Novel approach to olfactory-based spatial learning ability for preweaning mice and the effects of early exposure to diesel exhaust origin secondary organic aerosol
    Presenter : Tin-Tin-Win-Shwe, Chaw Kyi Tha Thu, Yadanar Moe, Fujitani Y., Shinji Tsukahara, Maekawa F., Hirano S.
    Name of Society : 44th Myanmar Health Research Congress (2016)
    Name of Proceedings : Abstract, 79
  • Research Presentation
    PRENATAL ARSENIC EXPOSURE IMPAIRED BEHAVIORAL FLEXIBILITY AND MORPHOLOGY OF CORTEX IN MICE
    Presenter : Maekawa F., KYAW HTET AUNG, CHAW KYI THA THU, Sano K., NAKAMURA S., Tanoue A., Kakeyama M., Tohyama C., Nohara K., Tsukahara S.
    Name of Society : 9th World Congress International Brain Research Organization (2015)
    Name of Proceedings : Abstracts, (301)
  • Research Presentation
    Adipose tissue malfunction in prenatally arsenic-exposed mice
    Presenter : Sano K., Maekawa F., Murai H., Nohara K.
    Name of Society : The Joint Meeting of the 120th Annual Meeting of The Japanese Association of Anatomists, the 92nd Annual Meeting of The Physiological Society of Japan. (2015)
    Name of Proceedings : The Journal of Physiological Sciences, 65(Supplement 1):S235
  • Research Presentation
    Effect of developmental exposure to acetamiprid on behavioral profiles in mice
    Presenter : Sano K., Yang J., Tin-Tin-Win-Shwe, Nohara K., Maekawa F.
    Name of Society : The 8th congress of the federation of the asian and oceanian physiological societies (2015)
    Name of Proceedings : Abstracts, 65(Supplemental 2):S-A179
  • Research Presentation
    Effect of prenatal exposure to arsenic on cell number and morphology of neuron in prelimbic cortex of adult mice
    Presenter : Kyaw Htet Aung, Maekawa F., Chaw Kyi Tha Thu, Sano K., Nakamura K, Tanoue A, Kakeyama M, Nohara K., Tsukahara S
    Name of Society : 21st Japanese Society for Behavioral Neuroendocrinology (2014)
    Name of Proceedings : Abstracts, 17
  • Research Presentation
    Effects of developmental exposure to diesel engine exhaust origin secondary organic aerosol on social and learning behavior in adult mice
    Presenter : Tin-Tin-Win-Shwe, Maekawa F., Chaw Kyi Tha Thu, Fujitani Y., Yanagisawa R., Furuyama A., Tsukahara S, Nohara K., Nitta H., Hirano S.
    Name of Society : 37th Annual Meeting of the Japan Neuroscience Society (2014)
    Name of Proceedings : Abstract, 131
  • Research Presentation
    Live imaging analysis of sodium arsenite-induced inhibition of neurite outgrowth in Neuro-2a cells
    Presenter : Aung K.H., Kurihara R., Nakashima S., Maekawa F., Nohara K., Kobayashi T., Tsukahara S.
    Name of Society : 分子予防環境医学研究大会第12回 (2013)
    Name of Proceedings : 同予稿集, 35
  • Research Presentation
    The Effects of Gestational Inorganic Arsenic Exposure in the Offspring and Future Generations
    Presenter : Nohara K., Suzuki T., Takumi S., Okamura K., Maekawa F.
    Name of Society : NIES Arsenic Workshop 2013 (2013)
    Name of Proceedings : Abstracts, 15
  • Research Presentation
    Effects of Perinatal Arsenic Exposure on the Development of Mice Brain
    Presenter : Maekawa F., Tsukahara S., Nohara K.
    Name of Society : NIES Arsenic Workshop 2013 (2013)
    Name of Proceedings : Abstracts, 21
  • Research Presentation
    Evaluation of sodium arsenite-induced inhibition of neurite outgrowth by live cell imaging and alteration of cytoskeletal gene expression in Neuro-2a cells
    Presenter : Aung K.H., Kurihara R., Nakashima S., Maekawa F., Nohara K., Kobayashi T., Tsukahara S.
    Name of Society : 日本行動神経内分泌研究会第17回 (2012)
    Name of Proceedings : 同予稿集, (5-1)
  • Research Presentation
    Late increases in tumorigenic stress and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic
    Presenter : Nohara K., Suzuki T., Tateishi Y., Okamura K., Murai H., Takumi S., Maekawa F., Nishimura N., Ito T.
    Name of Society : Prenatal Programming and Toxicity（PPTOX）? Meeting (2012)
    Name of Proceedings : Abstracts
  • Research Presentation
    Late-onset gene expression changes in the livers of male C3H mice maternally exposed to arsenic: Implications for an increase in hepatic tumor incidence
    Presenter : Nohara K., Tateishi Y., Suzuki T., Murai H., Takumi S., Okamura K., Maekawa f. , Nishimura N., Ito T.
    Name of Society : SOCIETY OF TOXICOLOGY 51st Annual Meeting (2012)
    Name of Proceedings : Abstracts of SOCIETY OF TOXICOLOGY 51st Annual Meeting
  • Research Presentation
    Impairment of glutamate AMPA receptor expression by sodium arsenite is related to the neurite suppression in mouse cortical neurons.
    Presenter : Maekawa F., Tsuboi T., Tsukahara S., Nohara K.
    Name of Society : NEUROSCIENCE 2012 42nd annual meeting (2012)
    Name of Proceedings : -
  • Research Presentation
    The effect of AMPA receptor overexpression on suppressed neurite outgrowth by sodium arsenite in mouse cortical neuron
    Presenter : Maekawa f. , Tsuboi T, Nohara K.
    Name of Society : The 34th Annual Meeting of the Japan Neuroscience Society (2011)
    Name of Proceedings : Abstracts of The 34th Annual Meeting of the Japan Neuroscience Society, s19
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  • Early developmental exposure to environmental chemicals and energy metabolism
    Presenter : Maekawa F.
    Name of Society : NIPS international workshop “Sensing food/nutrient/environment toward integrative metabolic regulation” (2019)
    Name of Proceedings : Abstracts, 24
  • Estrogenic action by tris(2,6-dimethylphenyl) phosphate, an impurity in flame retardant formulations, impairs the development of female reproductive functions
    Presenter : Maekawa F., Sano K., Suzuki G., Matsukami H., Tsukahara S.
    Name of Society : The 3rd Sino-Japan Symposium on the frontier of Behavioral Neuroendocrinology (2019)
    Name of Proceedings : Abstracts
  • Developmental exposure to a neonicotinoid affects certain behavioral parameters of mice in adulthood: Requirement of evaluation of socio-sexual and emotional behaviors using animal models
    Presenter : Maekawa F.
    Name of Society : Symposium on Systemic Pesticides Post-Neonics -What Next? (2016)
    Name of Proceedings : Abstracts
  • Experimental approaches toward understanding the association between early-life exposure to environmental chemicals and developmental disorders
    Presenter : Maekawa F.
    Name of Society : INTERNATIONAL SYMPOSIUM ON AUTISM 2017: CELEBRATING BRIMS 10TH YEAR ANNIVERSARY (2017)
    Name of Proceedings : Abstracts, 14-15
  • In vivo evaluation of a flame retardant having estrogenic activity using mouse model
    Presenter : Sano K., Suzuki G., Htike N.T.T., Morishita M., Tin-Tin-Win-Shwe, Hashimoto S., Kawashima T., Isobe T., Nakayama S., Tsukahara S., Maekawa F.
    Name of Society : Application of Recent Advances in Neuroscience to Environmental Health Research (2016)
    Name of Proceedings : abstract, 1-4
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